Drug delivery device with a module for preventing...

A - Human Necessities – 61 – M

Patent

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Details

A61M 5/142 (2006.01) A61M 5/165 (2006.01) A61M 5/38 (2006.01)

Patent

CA 2726839

The invention relates to a drug delivery device (1, 100), in particular for the delivery of drugs comprising molecules tending to spontaneously form nucleation seeds leading to fibrils, comprising a drug reservoir (2, 102) having a reservoir outlet (107) connected to a device outlet, adapted to deliver a drug fluid to a patient's body, through a pathway (5) including a fluid flow controlling system (4, 104). The pathway further includes a filtration module (6, 106) adapted to retain the nucleation seeds, preferably by forcing them through a filtering membrane pores and on the basis of hydrophobic interaction with the membrane.

L'invention concerne un dispositif (1, 100) d'administration de médicament, en particulier destiné à administrer des médicaments qui contiennent des molécules qui tendent à former spontanément des germes de nucléation conduisant à des fibrilles, et qui comprend un réservoir (2, 102) à médicament dont une sortie de réservoir (107) est reliée à une sortie de dispositif adaptée pour administrer un fluide médicamenteux dans le corps d'un patient par un parcours (5) qui contient un système (4, 104) de contrôle d'écoulement du fluide. Le parcours comprend en outre un module de filtration (6, 106) adapté pour retenir les germes de nucléation, de préférence en les refoulant à travers des pores d'une membrane de filtration sur base d'interactions hydrophobes avec la membrane.

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