A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01)
Patent
CA 2747505
Drug delivery devices comprising a non-bioabsorbable polymer structure and a composition comprising an active agent have been discovered. The drug delivery devices may be used to treat ocular conditions, among other diseases and condi-tions. In addition, a method of treating an ocular condition has been discovered comprising implanting a drug delivery device which releases the active agent at a rate of Q = 0.001 x N x C wherein C is the topical effective concentration (in milligram/mL) of the active agent and N=0.01 to 0.5 for prostaglandins in their ester, amide, free acid or salt form, and N=0.5 to 5 for any active agent other than prostaglandins in their ester, amide, free acid or salt form.
L'invention concerne des dispositifs d'administration de médicaments comprenant une structure polymère non bioabsorbables et une composition comprenant un agent actif. Les dispositifs d'administration de médicaments peuvent être utilisés pour traiter des états oculaires, entre autres maladies et états. En outre, l'invention concerne un procédé de traitement d'un état oculaire qui comprend l'implantation d'un dispositif d'administration de médicaments qui libère l'agent actif à un taux Q = 0,001 x N x C, C étant la concentration efficace topique (en milligramme/ml) de l'agent actif et N=0,01 à 0,5 pour les prostaglandines sous leur forme ester, amide, acide libre ou sel, et N=0,5 à 5 pour tout agent actif autre que des prostaglandines sous leur forme ester, amide, acide libre ou sel.
Kopczynski Casey
Lin Cheng-Wen
Sutay Chris
Aerie Pharmaceuticals Inc.
Ledgley Law
LandOfFree
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