Drug delivery from a polymer coating on a medical device

Details Drug delivery from a polymer coating on a medical device Drug delivery from a polymer coating on a medical device

A - Human Necessities

61

L

A61L 31/10 (2006.01) A61L 27/34 (2006.01) A61L 27/44 (2006.01) A61L 29/08 (2006.01) A61L 29/12 (2006.01) A61L 29/16 (2006.01) A61L 31/16 (2006.01) C08L 33/08 (2006.01) C08L 33/10 (2006.01) C08L 33/12 (2006.01)

Patent

CA 2519503

Methods of making a coating on a medical device are disclosed, including associating a composition with at least a portion of the device to form a layer. In some embodiments, a composition may include a copolymer prepared from a room temperature melt of a plurality of monomer units that comprises a first monomer unit and a second monomer unit, wherein the second monomer unit has a glass transition temperature that is at least about 30 degrees Centigrade higher than the glass transition temperature of the first monomer unit, with a glass transition temperature of a monomer unit being defined as a glass transition temperature of a homopolymer of that monomer unit.

Procédé de formation d'un revêtement sur un dispositif médical, consistant à associer une composition à au moins une partie du dispositif afin de former une couche. Dans certains modes de réalisation, une composition peut comprendre un copolymère préparé à partir d'un bain de fusion à température ambiante de plusieurs motifs monomères comportant un premier motif monomère et un second motif monomère, le second motif monomère ayant une température de transition vitreuse supérieure d'au moins environ 30 ·C à celle du premier motif monomère, et la température de transition vitreuse d'un motif monomère étant définie comme étant la température de transition vitreuse d'un homopolymère du motif monomère en question.

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