A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/436 (2006.01) A61L 29/16 (2006.01) A61L 31/16 (2006.01) A61M 31/00 (2006.01) A61P 29/00 (2006.01) C07D 498/16 (2006.01)
Patent
CA 2511573
A drug delivery device or system comprising: a) a medical device, e.g. a coated stent or stent-graft, adapted for local application or administration in hollow tubes; and, in conjunction therewith, b) a therapeutic dosage of an anti-inflammatory ascomycin derivative, such as pimecrolimus, e.g. affixed to the medical device, and use thereof in the preparation of a medicament for the prevention and treatment of inflammatory complications following vascular injury, and method of treatment therewith.
L'invention porte sur un système d'administration de médicaments comportant: (a) un dispositif médical tel qu'un stent enduit ou un stent/greffe pour application locale ou administration dans des tubes creux; et (b), lui étant associé, une dose thérapeutique d'un dérivé anti-inflammatoire d'ascomycine tel que le pimecrolimus, fixé par exemple au dispositif médical. L'invention porte sur l'utilisation dudit système pour la préparation d'un médicament prévenant et traitant les complications à caractère inflammatoire consécutives à un accident vasculaire, et sur les méthodes de traitement associées.
Fetherstonhaugh & Co.
Novartis Ag
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