Drug delivery system

Details Drug delivery system Drug delivery system

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/24 (2006.01) A61K 31/565 (2006.01) A61P 15/18 (2006.01) A61P 31/18 (2006.01)

Patent

CA 2524665

The subject invention provides a drug delivery system comprising at least one compartment consisting of (i) a drug-loaded thermoplastic polymer core, (ii) a drug-loaded thermoplastic polymer intermediate layer and (iii) a non-medicated thermoplastic polymer skin covering the intermediate layer, wherein said intermediate layer is loaded with (a) crystals of a first pharmaceutically active compound and with (b) a second pharmaceutically active compound in dissolved form and wherein said core is loaded with said second compound in dissolved form.

L'invention concerne un système d'administration de médicaments qui comprend au moins un compartiment constitué (i) d'un noyau polymère thermoplastique chargé de médicaments, (ii) d'une couche intermédiaire polymère thermoplastique chargée de médicaments et (iii) d'un film polymère thermoplastique non médicamenteux recouvrant la couche intermédiaire. Ladite couche intermédiaire est chargée (a) de cristaux d'un premier composé pharmaceutiquement actif et (b) d'un second composé pharmaceutiquement actif sous forme dissoute, ledit noyau étant chargé dudit second composé sous forme dissoute.

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