Drug delivery system using subconjunctival depot

A - Human Necessities – 61 – K

Patent

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A61K 9/06 (2006.01) A61K 9/00 (2006.01) A61K 9/10 (2006.01) A61K 31/00 (2006.01) A61K 31/573 (2006.01) A61K 47/12 (2006.01) A61K 47/34 (2006.01) A61K 47/38 (2006.01) A61P 27/02 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2508303

A drug delivery system for posterior segment of eyeball in which subconjunctival administration of a phamaceutical composition comprising a drug and a base is effected so as to attain formation of a depot using a base material and in which sustained release of the drug from the depot is carried out so as to realize maintaining of effective drug concentration. This phamaceutical composition comprises a base being in the form of a gel under the conjunctiva and a drug suspended in the base.

L'invention a trait à un système d'administration de médicament destiné au segment postérieur du globe oculaire. Selon ledit système, l'administration sous-conjonctivale d'une composition pharmaceutique contenant un médicament et une base est effectuée de manière à obtenir la formation d'un dépôt par l'intermédiaire d'une matière de base, et la libération prolongée du médicament du dépôt est réalisée de manière que soit maintenue une concentration de médicament efficace. La composition pharmaceutique selon l'invention contient une base sous forme de gel placée sous la conjonctive et un médicament en suspension dans ladite base.

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