Drug delivery system with stabilising effect

Details Drug delivery system with stabilising effect Drug delivery system with stabilising effect

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/70 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2714598

A drug delivery system also intended as unit dosage form comprising a thin water-soluble film matrix, wherein said film matrix comprises a) a polyvinyl alcohol-polyethylene glycol graft copolymer (PVA-PEG graft copolymer) as a water-sol-uble matrix polymer; b) an active ingredient being a steroid in which the positions 6 and 7 of the steroidal skeleton are both a -CH2- residue; and said film matrix has a thickness of less than 300 µm.

Linvention concerne un système d'administration de médicament servant également de forme posologique unitaire, qui comprend une matrice pelliculaire mince soluble dans l'eau contenant: a) un copolymère greffé d'alcool polyvinylique et de polyéthylèneglycol (copolymère greffé PVA-PEG) comme matrice polymère soluble dans l'eau; b) un ingrédient actif qui est un stéroïde dans lequel les positions 6 et 7 du squelette stéroïdien sont tous deux un résidu -CH2-, cette matrice pelliculaire présentant une épaisseur inférieure à 300 µm.

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