Drug delivery through application in nails

A - Human Necessities – 61 – B

Patent

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A61B 18/20 (2006.01)

Patent

CA 2577545

A method for delivering a pharmaceutical composition to a human or animal nail, said method comprising forming several partial orifices in a nail with an appropriate device and applying a pharmaceutical composition in the orifices. Preferably the device comprises a laser programmed in a way to drill arrays of partial orifices where each partial orifices can be drilled with a single laser shot or, optionally with several laser shots. Preferably the partial orifices have similar depths across the nail. The method of the invention allows for the continuous treatment of diseases over a period of time with a minimum of patient discomfort combined with a high degree of efficacy.

L'invention porte sur un procédé qui permet d'administrer une composition pharmaceutique par application sur un ongle humain ou animal, lequel procédé consiste à former plusieurs orifices partiels dans un ongle à l'aide d'un dispositif approprié et à appliquer une composition pharmaceutique dans les orifices. De préférence, le dispositif comprend un laser programmé de manière qu'il perce des réseaux d'orifices partiels, chaque orifice partiel pouvant être percé par une seule décharge laser ou, facultativement, par de multiples décharges laser. De préférence, les orifices partiels possèdent des profondeurs similaires sur toute la surface de l'ongle. Le procédé de l'invention permet de réaliser le traitement de maladies de manière continue pendant une période de temps, avec un minimum d'inconfort pour le patient et un haut degré d'efficacité.

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