Drug dispensing wound dressing

Details Drug dispensing wound dressing Drug dispensing wound dressing

A - Human Necessities

61

L

167/156

A61L 15/44 (2006.01) A61L 15/26 (2006.01) A61F 13/15 (2006.01)

Patent

CA 1255224

ABSTRACT OF THE DISCLOSURE The disclosed wound dressings have a drug dispersed throughout a polyurethane matrix that is the reaction product of: (A) An isocyanate terminated prepolymer formed by reaction of isophorone diisocyanate and a macroglycol and (B) a monomer containing hydroxyl and vinyl groups. The reaction product is a vinyl terminated polyurethane oligomer which is liquid at room temperature and which may be readily admixed with a pharmacoactive substance and a photosensitizer, formed into a film and cured by exposure to UV light without release of heat. In the most preferred embodiments the foregoing oligomer is codissolved in an organic solvent with a polyurethane polymer which is the reaction product of: dicyclohexyl methane diisocyanate; a polytetramethylene ether polyol having a molecular weight in the range of 1000-3000 Daltons; and 1,4-butane diol. That solution is then admixed with the pharmacoactive agent, formed into a film and cured.

495122

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