Drug for curing or preventing mood disorder or anxiety disorder

A - Human Necessities – 61 – K

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A61K 31/4745 (2006.01) A61K 31/4985 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2414971

Therapeutic or preventive medicines for mood disorders or anxiety disorders which contain as the active ingredient isoquinoline derivatives including (4aS, 12aS)-2-methyl-4a-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12a-octahydroquinolino[2,3-g]isoquinoline or pharmacologically acceptable acid addition salts thereof and are lowered in the side effects; methods for treatment or prevention of mood disorders or anxiety disorders by using the medicines; and use of the derivatives or the salts in preparing therapeutic or preventive medicines for mood disorders or anxiety disorders.

L'invention concerne des médicaments préventifs ou thérapeutiques contre les troubles de l'humeur ou les troubles anxieux, qui contiennent, en tant que principe actif, des dérivés d'isoquinoline comprenant (4aS, 12aS)-2-méthyl-4a-(3-hydroxyphényl)-1,2,3,4,4a,5,12,12a-octahydroquinolino[2,3-g]isoquinoline ou des sels d'addition acide pharmacologiquement acceptables présentant des effets secondaires réduits. L'invention concerne en outre l'utilisation de ces dérivés ou sels dans la préparation de médicaments préventifs ou thérapeutiques contre les troubles de l'humeur ou les troubles anxieux.

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