A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61P 3/10 (2006.01) C07K 16/18 (2006.01)
Patent
CA 2756853
The present invention relates to drug fusions that have improved serum half lives. These fusions and conjugates comprise polypeptides, immunoglobulin (antibody) single variable domains and GLP and/or exendin molecules. The invention further relates to uses, formulations, compositions and devices comprising such drug fusions and conjugates.
La présente invention concerne des fusions de médicament qui possèdent des demi-vies sériques améliorées. Lesdites fusions et lesdits conjugués comprennent des polypeptides, des domaines variables uniques d'immunoglobuline (anticorps) et des molécules d'exendine et/ou de GLP. L'invention concerne en outre des utilisations, des formulations, des compositions et des dispositifs comprenant de telles fusions de médicaments et de tels conjugués.
Herring Christopher
Holt Lucy J.
Jespers Laurent S.
Mayer Sebastian
Pupecka-Swider Malgorzata
Glaxo Group Limited
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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