Drug fusions and conjugates

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) A61P 3/00 (2006.01) A61P 3/10 (2006.01) C07K 14/605 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2718480

The present invention relates to drug fusions that have improved serum half lives. These fusions and conjugates comprise polypeptides, immunoglobulin (antibody) single variable domains and GLP and/or exendin molecules. The invention further relates to uses, formulations, compositions and devices comprising such drug fusions and conjugates.

La présente invention concerne des fusions médicamenteuses qui présentent des demi-vies sériques améliorées. Ces fusions et ces conjugués comprennent des polypeptides, des domaines variables uniques (anticorps) de limmunoglobuline et des GLP et/ou des molécules dexendin. Linvention porte en outre sur des utilisations, des formulations, des compositions et des dispositifs comprenant de telles fusions médicamenteuses et de tels conjugués médicamenteux.

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