Drug metabolizing enzymes

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) A01K 67/027 (2006.01) A61K 38/43 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/14 (2006.01) C12N 9/16 (2006.01) C12N 9/78 (2006.01) C12N 15/53 (2006.01) C12N 15/54 (2006.01) C12Q 1/25 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2438740

The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.

L'invention concerne des enzymes humaines métabolisant un médicament (DME) et des polynucléotides qui identifient et codent pour DME. L'invention concerne aussi des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes ; ainsi que des procédés permettant de diagnostiquer, de traiter ou de prévenir des troubles associés à une expression aberrante de DME.

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