C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) A01K 67/027 (2006.01) A61K 38/44 (2006.01) A61K 38/45 (2006.01) C07K 16/40 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2429199
The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with aberrant expression of DME.
La présente invention concerne des enzymes de métabolisation de médicaments (DME) humaines et des polynucléotides qui identifient et codent ces enzymes. Cette invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes. Par ailleurs, l'invention concerne des méthodes diagnostiques, thérapeutiques et prophylactiques des troubles associés à l'expression aberrante des enzymes de métabolisation de médicaments.
Arvizu Chandra
Baughn Mariah R.
Bruns Christopher M.
Burford Neil
Chawla Narinder K.
Incyte Genomics Inc.
Smart & Biggar
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