Drug metabolizing enzymes

Details Drug metabolizing enzymes Drug metabolizing enzymes

C - Chemistry, Metallurgy

12

N

C12N 15/60 (2006.01) A01K 67/00 (2006.01) A61K 38/17 (2006.01) A61K 38/44 (2006.01) A61K 38/45 (2006.01) A61K 38/46 (2006.01) A61K 38/51 (2006.01) A61K 38/53 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 16/40 (2006.01) C12N 9/00 (2006.01) C12N 9/02 (2006.01) C12N 9/10 (2006.01) C12N 9/18 (2006.01) C12N 9/78 (2006.01) C12N 9/88 (2006.01) C12N 15/12 (2006.01) C12N 15/52 (2006.01) C12N 15/53 (2006.01) C12N 15/54 (2006.01) C12N 15/55 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (20

Patent

CA 2453075

Various embodiments of the invention provide human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.

Divers modes de réalisation de cette invention concernent des enzymes humaines de métabolisation de médicaments et des polynucléotides qui identifient et codent lesdites enzymes. Certains modes de réalisation de l'invention ont trait à des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes, et des antagonistes. D'autres modes de réalisation portent sur des méthodes de diagnostic, de traitement ou de prévention de troubles liés à l'expression aberrante des enzymes de métabolisation de médicaments.

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