G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/94 (2006.01)
Patent
CA 2699062
A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invention also pertains to the respectively created binding agents and derivatives. Furthermore, drug monitoring assays using said binding agents for monitoring pharmaceutically active forms of said parent compound are provided.
La présente invention concerne un procédé d'obtention d'au moins un agent de liaison qui se lie à une forme pharmaceutiquement active du composé avec une spécificité supérieure à celle d'une forme pharmaceutiquement inactive dudit composé, grâce à l'utilisation de dérivés spéciaux dudit composé parent. L'invention concerne également les agents de liaison respectivement créés et leurs dérivés. En outre, l'invention porte sur des tests de pharmacovigilance utilisant lesdits agents de liaison pour permettre la surveillance des formes pharmaceutiquement actives dudit composé parent.
Albientz Patrick
Grenet Jean-Miche
Hillenbrand Rainer
Legay Francois
Marbach Peter
Fetherstonhaugh & Co.
Novartis Ag
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