Drug particles having constant release

Details Drug particles having constant release Drug particles having constant release

A - Human Necessities

61

K

167/240, 167/262

A61K 9/56 (2006.01) A61K 9/50 (2006.01) A61K 31/19 (2006.01)

Patent

CA 1275049

ABSTRACT DRUG PARTICLES HAVING CONSTANT RELEASE Drug particles are disclosed which reduce the variation in dissolution rate with time frequently found with sustained-release dosage forms. This is achieved by coating the drug particle, which may contain a surfactant and a disintegrant in addition to the drug active, with a first coating of a water soluble polymer, a second coating of an enteric material and a third coating of a material which is insoluble at any pH and acts as a diffusion barrier for the drug active.

516080

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