Drug release stent coating process

Details Drug release stent coating process Drug release stent coating process

A - Human Necessities

61

L

A61L 31/16 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 31/10 (2006.01) A61L 33/10 (2006.01) C08J 3/24 (2006.01) C08J 7/04 (2006.01)

Patent

CA 2598946

A method of coating implantable open lattice metallic stent prosthesis is disclosed which includes sequentially applying a plurality of relatively thin outer layers of a coating composition comprising a solvent mixture of uncured polymeric silicone material and crosslinker and finely divided biologically active species, possibly of controlled average particle size, to form a coating on each stent surface. The coatings are cured in situ and the coated, cured prostheses are sterilized in a step that includes preferred pretreatment with argon gas plasma and exposure to gamma radiation electron beam, ethylene oxide, steam.

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