A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 9/10 (2006.01) A61K 35/76 (2006.01) A61K 38/18 (2006.01) A61K 47/34 (2006.01) A61K 51/00 (2006.01)
Patent
CA 2523620
The present invention relates to fiber compositions comprising gels or hydrogels. The invention further relates to the composition of a gel or hydrogel loaded biodegradable fiber and methods of fabricating such fibers. The present invention further provides tissue engineering and drug-delivery compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The invention also relates to methods of manipulating the rate of therapeutic agent release by changing both the biodegradable polymer properties as well as altering the properties of the incorporated gel or hydrogel.
L'invention concerne : des compositions de fibres qui comprennent des gels ou des hydrogels ; la composition d'une fibre biodégradable chargée de gel ou d'hydrogel ainsi que des procédés de fabrication desdites fibres ; des compositions de génie tissulaire et d'administration de médicaments et des procédés dans lesquels des matrices tridimensionnelles destinées à la culture de cellules sont préparées pour un usage in vitro et in vivo ; enfin, des procédés qui permettent de manipuler le taux de libération d'agents thérapeutiques en modifiant les propriétés du polymère biodégradable et en altérant les propriétés du gel ou de l'hydrogel incorporé.
Crow Brent B.
Nelson Kevin D.
Board Of Regents - The University Of Texas System
Marks & Clerk
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