A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61L 27/54 (2006.01) A61L 27/58 (2006.01) D01F 1/10 (2006.01) D01F 6/62 (2006.01) D01F 8/14 (2006.01) D06M 15/03 (2006.01) D06M 16/00 (2006.01) A61K 9/00 (2006.01)
Patent
CA 2379909
The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal distribution of released therapeutic agents is controlled by use of defined nonhomogeneous patterns of therapeutic agents in the matrices.
L'invention concerne des compositions de génie tissulaire et des procédés associés. Des matrices tridimensionnelles pour cultiver des cellules sont préparées pour utilisation in vitro et in vivo. Ces matrices comportent des fibres polymères biodégradables capables de libérer des agents thérapeutiques. La distribution spatiale et temporelle des agents thérapeutiques libérés est régulée par l'emploi de motifs non homogènes d'agents thérapeutiques dans les matrices.
Alikacem Nadir
Hu Zhibing
Nelson Kevin D.
Radulescu Delia
Romero-Sanchez Andres A.
Board Of Regents The University Of Texas System
Marks & Clerk
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