Drug safety test using pentraxin-3 (ptx-3)

Details Drug safety test using pentraxin-3 (ptx-3) Drug safety test using pentraxin-3 (ptx-3)

G - Physics

01

N

G01N 33/543 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2727059

The invention relates to an in vitro method for assessing the immunogenicity of a compound of interest comprising the steps of: a) providing a whole blood sample, wherein said blood was exposed to said compound of interest, b) measuring the level of pentraxin-3 in said sample, and c) comparing the measured level of pentraxin-3 with a control.

La présente invention concerne un procédé in vitro permettant dévaluer limmunogénicité dun composé dintérêt, le procédé consistant à : a) utiliser un échantillon de sang entier, ledit sang ayant été exposé audit composé d'intérêt, b) mesurer le niveau de la pentraxine-3 contenue dans ledit échantillon, et c) comparer le niveau de pentraxine-3 mesuré à un groupe témoin.

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