Drug signatures

Details Drug signatures Drug signatures

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/68 (2006.01) G01N 33/94 (2006.01) G06F 17/30 (2006.01) G06F 19/00 (2006.01) G06F 17/60 (2000.01)

Patent

CA 2477239

Methods for deriving and using Group Signatures and Drug Signatures are provided, wherein Group Signatures comprise a plurality of genes, modulated expression of which is characteristic and specific of a group of related drug compounds, and wherein Drug Signatures comprise a plurality of genes, modulated expression of which is characteristic and specific for individual drug compounds.

L'invention concerne des méthodes de formation et d'utilisation de signatures de groupe et de signatures de médicaments. Les signatures de groupe comprennent une pluralité de gènes dont l'expression modulée est caractéristique et spécifique d'un groupe de composés de médicaments associés. Les signatures de médicaments comprennent une pluralité de gènes dont l'expression modulée est caractéristique et spécifique de composés de médicaments individuels.

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