A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/40 (2006.01) A23L 1/305 (2006.01) A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01) A61K 9/30 (2006.01) A61K 9/32 (2006.01) A61K 9/34 (2006.01) A61K 9/36 (2006.01) A61K 9/48 (2006.01) A61K 38/43 (2006.01) A61K 38/46 (2006.01) A61K 38/47 (2006.01) A61K 38/55 (2006.01) A61K 39/395 (2006.01) A61K 47/32 (2006.01) A61K 47/38 (2006.01) A61K 47/42 (2006.01) A61K 47/46 (2006.01) A61P 1/00 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 9/12 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2429649
Drugs and foods processed so as to effectively exert physiological activities, in case of orally administering physiologically active protein(s). Compositions for oral administration which contain one or more physiologically active proteins as the active ingredient and provided with a release- controlling means. Use of these compositions makes it possible to deliver at least 10% of the active ingredient to the lower digestive tract while sustaining the physiological activities. Since the physiologically active proteins are not digested in the stomach but delivered to the small intestine, it becomes possible to exert an effect which has been unknown so far or to ensure the achievement of an effect. Preferable examples of the physiologically active proteins contained in these compositions include lactoferrin, immunoglobulin, lysozyme, amylase, protease, lipase and digestive enzyme inhibitors.
L'invention porte sur des médicaments et des aliments traités de manière à avoir un effet physiologique efficace lors d'une administration orale de protéine(s) physiologiquement active(s). L'invention porte également sur des compositions d'administration orale contenant une ou plusieurs protéine(s) physiologiquement active(s) tenant lieu de principe actif et présentant des moyens de contrôle de la libération. Ces compositions permettent de libérer au moins 10 % du principe actif dans le tractus inférieur digestif, l'effet physiologique étant durable. Les protéines physiologiquement actives n'étant pas digérés dans l'estomac mais libérées dans le petit intestin, elles ont un effet qui est encore inconnu de nos jours ou elles peuvent assurer la bonne marche de l'effet physiologique. L'invention recense de préférence certains exemples de protéines physiologiquement actives contenues dans ces compositions, dont la lactoférine, l'immunoglobuline, la lysozyme, l'amylase, la protéase, la lipase et des inhibiteurs d'enzyme digestive.
Ando Kunio
Fukuda Akio
Igusa Kazuo
Kawai Juri
Ogasawara Toshichika
Nuclear Receptor Ligand Co. Ltd.
Robic
LandOfFree
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