Drugs comprising chymase inhibitors and ace inhibitors as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 409/06 (2006.01) A61K 31/216 (2006.01) A61K 31/401 (2006.01) A61K 31/404 (2006.01) A61K 31/405 (2006.01) A61K 31/4174 (2006.01) A61K 31/4184 (2006.01) A61K 31/472 (2006.01) A61K 31/551 (2006.01) A61K 31/554 (2006.01) A61K 31/662 (2006.01) A61P 9/00 (2006.01) C07D 235/28 (2006.01) C07D 403/06 (2006.01)

Patent

CA 2442761

It is intended to provide drugs efficacious in treating hypertension, heart diseases (megalocardia, heart failure, myocardial infarction, etc.), cerebral attack, nephritis and the like. Namely, remedies for circulatory diseases wherein a chymase inhibitor and an ACE inhibitor can be used together; and a method of treating circulatory diseases associated with the simultaneous occurrence of chymase inhibition and ACE inhibition.

La présente invention concerne des médicaments efficaces pour traiter l'hypertension, les maladies cardiaques (cardiomégalie, insuffisance cardiaque, infarctus du myocarde, etc.), les crises cérébrales, les néphrites et analogues. L'invention se rapporte en particulier à des remèdes contre les maladies circulatoires dans lesquels un inhibiteur de la chymase et un inhibiteur de l'ACE peuvent être utilisés ensemble, et à un procédé de traitement des maladies circulatoires associé à l'occurrence simultanée d'une inhibition de la chymase et d'une inhibition de l'ACE.

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