Dry compositions containing hydrophobic amino acid

Details Dry compositions containing hydrophobic amino acid Dry compositions containing hydrophobic amino acid

C - Chemistry, Metallurgy

09

K

C09K 15/16 (2006.01) A61K 9/19 (2006.01) A61K 38/00 (2006.01) A61K 38/21 (2006.01) A61K 47/18 (2006.01) A61K 47/26 (2006.01) A61P 7/06 (2006.01) A61P 31/12 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2395438

The invention provides an amino acid usable for reducing and/or preventing the coloration caused by a combined use of saccharide and amino acid, and an amino acid usable as a stabilizer for a dry composition containing a pharmacologically active proteinaceous substance. The invention also provides an anti-coloring agent containing a hydrophobic amino acid as an essential ingredient suitable for preventing the coloration of a dry composition containing a saccharide, a method for preventing the coloration of a dry composition containing a saccharide using a hydrophobic amino acid, and a dry composition containing a pharmacologically active proteinaceous substance which further comprises a saccharide and a hydrophpbic amino acid as a stabilizer.

L'invention concerne un acide aminé utilisé pour réguler ou empêcher la coloration provoquée par l'utilisation combinée de saccharides et d'acides aminés; et un acide aminé utilisé comme stabilisateur pour des compositions sèches contenant une substance protéique pharmacologiquement active. L'invention concerne également un inhibiteur de coloration contenant principalement un acide aminé hydrophobe et qui permet d'empêcher la coloration des compositions sèches contenant des saccharides; un procédé servant à empêcher la coloration des compositions sèches contenant des saccharides, consistant à utiliser un acide aminé hydrophobe; et des compositions sèches contenant une substance protéique pharmacologiquement active, contenant également des saccharides et un acide aminé hydrophobe comme stabilisateur.

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