Dry gel pharmaceutical composition

Details Dry gel pharmaceutical composition Dry gel pharmaceutical composition

A - Human Necessities

61

K

A61K 47/36 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 31/495 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2116563

There is provided a dry gel,composition comprising 40 % by weight or below of a medicine which can be orally administered, 3 % by weight or above of a gelling agent and 5 % by weight or below of a binder, which composition is capable of forming a gruel-like aqueous gel composition upon mixing with 2 to 15 parts by weight of water per part by weight of the composition at a temperature of 40°C or below. The gelling agent usable herein is, for example, pregelatinized starch having a concentration of 50 % by weight or above. The medicine which can be orally administered is, for example, cinnarizine. Upon mixing with a predetermined quantity of water, the dry gel composition forms a homogeneous aqueous gel composition having a viscosity of about 100 to 500 cp, which is preferably thixotropic. Even aged people having a weak swallowing function can easily swallow the aqueous gel composition, without causing improper sucking into their tracheas. Thus, the dry gel composition of the present invention is very useful in their medical care. The aqueous gel composition can be prepared in a short time by an extremely simple operation at the time of use.

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