Dry matrices as drug reservoirs in electrotransport...

A - Human Necessities – 61 – N

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A61N 1/30 (2006.01)

Patent

CA 2634594

The present invention provides methods and devices for the electrotransport delivery of beneficial agents that utilize polymer electrolyte matrices as drug reservoirs. In certain aspects of the invention, the beneficial agents are hydrolytically unstable, and methods are provided for enhancing the stability of the hydrolytically unstable beneficial agents during long-term storage of devices for the electrotransport delivery of the hydrolytically unstable beneficial agents and during electrotransport delivery of the hydrolytically unstable beneficial agents.

La présente invention concerne des procédés et des dispositifs pour l'administration d'agents bénéfiques par électrotransport, des matrices électrolytes polymères étant utilisées comme réservoirs de médicaments. Dans certains aspects de l'invention, les agents bénéfiques sont hydrolytiquement instables et des procédés permettent d'accroître la stabilité de ces agents bénéfiques hydrolytiquement instables au cours du stockage à long terme de dispositifs pour l'administration desdits agents par électrotransport et au cours de l'administration desdits agents par électrotransport.

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