Dry polymer and lipid composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/30 (2006.01) A61K 9/20 (2006.01) A61K 31/57 (2006.01) A61K 47/12 (2006.01) A61K 47/24 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2519070

The present invention provides an orally administrable composition comprising a dry mixture of polymer, lipid and bioactive agent, being capable on contact with water or GI tract liquid of forming particles comprising said lipid and said bioactive agent and optionally also water. It is preferable that such particles have a liquid crystalline phase structure. The invention also provides a method for the formation of compositions comprising polymer, lipid and bioactive agent.

La présente invention concerne une composition pouvant être administrée par voie orale, contenant un mélange sec formé d'un polymère, un lipide et un agent bioactif, qui, lorsqu'il est mis en contact avec de l'eau ou le liquide du tractus gastro-intestinal, peut former des particules contenant ledit lipide et ledit agent bioactif et, éventuellement, également de l'eau. Ces particules possèdent, de préférence, une structure à phase cristalline liquide. L'invention concerne également un procédé de formation de compositions contenant un polymère, un lipide et un agent bioactif.

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