Dry powder compound formulations and uses thereof

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/14 (2006.01) A61K 9/19 (2006.01) A61K 9/20 (2006.01) A61K 31/485 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2661830

The present invention provides lyophilized formulations comprising methylnaltrexone, and processes for preparation of provided formulations. Additionally provided are compositions and products containing the methylnaltrexone formulation, as well as methods for producing formulations, compositions and products. Provided formulations as well as compositions and products containing methylnaltrexone formulations are useful for preventing, treating delaying, diminishing or reducing the severity and/or incidence of side effects resulting from administration of analgesic opioids.

La présente invention concerne des formulations lyophilisées à base de méthylnaltrexone, et les procédés d'élaboration des formulations considérées. L'invention concerne également des compositions et des produits contenant la formulation à la méthylnaltrexone, ainsi que des procédés de production de ces formulations, compositions et produits. Les formulations de l'invention ainsi que les compositions et les produits contenant la formulation à la méthylnaltrexone conviennent pour la prévention, le traitement, le retardement, la diminution ou l'atténuation de la gravité et/ou de l'incidence des effets secondaires résultant de l'administration d'opioïdes analgésiques.

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