Dry powder fibrin sealant

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/16 (2006.01) A61L 24/10 (2006.01)

Patent

CA 2761903

A fibrin sealant comprises a mixture of first microparticles that comprise fibrinogen, second microparticles that comprise thrombin, and additive material. The additive material may be particulate, and may be, for instance, a biocompatible, water- absorbent, material, a biocompatible, water-swellable material, a biocompatible, water-insoluble material, a polysaccharide or silica.

L'invention porte sur une colle de fibrine comprenant un mélange de premières microparticules qui comprennent du fibrinogène, de secondes microparticules qui comprennent de la thrombine et d'un additif. L'additif peut être particulaire et peut être, par exemple, une matière biocompatible absorbant l'eau, une matière biocompatible apte à gonfler avec l'eau, une matière biocompatible insoluble dans l'eau, un polysaccharide ou de la silice.

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