Dry-powder film coating composition and method of preparation

Details Dry-powder film coating composition and method of preparation Dry-powder film coating composition and method of preparation

A - Human Necessities

61

K

A61K 47/38 (2006.01) A23G 3/54 (2006.01) A23L 1/00 (2006.01) A23P 1/08 (2006.01) A61K 9/28 (2006.01) A61K 9/34 (2006.01) A61K 9/36 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2421399

An edible dry-powder formulation of a film coating for pharmaceuticals and confectionaries using gum acacia as a low-cost film former is provided. A cellulosic polymer such as hydroxypropyl methylcellulose is used in addition to the gum acacia. A plasticizer such as propylene glycol is also added. The resulting formulation is a dry, free flowing powder that can be put into solution and applied to a tablet or other substrate without an extended waiting period. The resulting film coating is clear, shiny, durable and extremely economical. Because the formulation is a dry powder, it has along shelf life and low shipping costs.

L'invention concerne une formulation de poudre sèche comestible pour former un film d'enrobage destiné à des médicaments et des produits de confiserie, cette formulation comprenant de la gomme arabique utilisée comme filmogène économique. Outre la gomme arabique, on utilise un polymère cellulosique tel que l'hydroxypropyl-méthylcellulose. On ajoute également un plastifiant tel que le propylèneglycol. La formulation obtenue est une poudre sèche à haute fluidité qui peut être utilisée en solution et appliquée sur un comprimé ou sur un autre substrat, sans période d'attente étendue. Le film d'enrobage obtenu est transparent, brillant, résistant et extrêmement économique. La formulation étant une poudre sèche, elle présente une durée de conservation étendue et un faible coût d'expédition.

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