Dry powder formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01)

Patent

CA 2542450

A dry powder suitable for inhalation in a dry powder inhaler, the powder comprising a carrier, an active agent and at least 0.5% by weight of magnesium stearate, the powder being further characterized in that the less than 10% of the surface of the carrier material is covered with particles of magnesium stearate . The invention is also directed to a method of making dry powders by blending together the ingredients mentioned in a diffusion blender for a period time that is less than 60 minutes.

Poudre sèche susceptible d'être inhalée au moyen d'un inhalateur à poudre sèche. Cette poudre comporte un excipient, un actif et au moins 0,5 % en poids de stéarate de magnésium, ladite poudre étant caractérisée également en ce que moins de 10 % de la surface du produit excipient est recouverte de particules de stéarate de magnésium. L'invention se rapporte également à un procédé de fabrication de poudre sèche par mélange des ingrédients précités dans un mélangeur à diffusion pendant une durée inférieure à 60 minutes.

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