Dry powder inhaler excipient, process for its preparation...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2287333

A pharmaceutical excipient useful in the formulation of dry powder inhaler compositions comprising a particulate roller-dried anhydrous .beta.-lactose, said .beta.-lactose particles having a size between 50 and 250 micrometers and a rugosity between 1.9 and 2.4, and the so formulated pharmaceutical compositions.

L'invention concerne un excipient pharmaceutique utile dans la formulation de compositions pour inhalateurs à poudre sèche, comprenant du beta -lactose anhydre particulaire séché dans des cylindres. Les particules de beta -lactose ont une taille comprise entre 50 et 250 mu m et une rugosité comprise entre 1,9 et 2,4. L'invention concerne également les compositions pharmaceutiques ainsi formulées.

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