Dry powder inhaler formulations comprising surface-modified...

A - Human Necessities – 61 – K

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A61K 9/12 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2589514

The present invention is concerned with a refinement of the processing of particles that are to form a dry powder formulation which is to be administered to the lung using a dry powder inhaler (DPI) device. In particular, the present invention provides the processing of particles of active material and particles of carrier material in the presence of additive material to provide a powder composition which exhibits excellent powder properties and which is economical to produce.

La présente invention concerne une amélioration du traitement de particules destinées à former une formulation en poudre sèche à administrer aux poumons à l'aide d'un dispositif inhalateur de poudre sèche (DPI). L'invention concerne notamment le traitement de particules de matière active et de particules de matière porteuse en la présence d'une matière d'additif pour produire une composition en poudre présentant d'excellentes propriétés de poudre et économique à produire.

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