C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/04 (2006.01) A61K 39/13 (2006.01) A61K 39/295 (2006.01)
Patent
CA 2503946
The present invention relates to a method of drying biological and other labile samples so that they can be preserved as a highly viscous liquid. The method involves the steps of preparing a preservation sample by dissolving/suspending an active agent in a solution of a stabilising agent, subjecting the preservation sample to such temperature and pressure conditions that the preservation sample looses solvent by evaporation without freezing or bubbling to form a foam and removing solvent until the preservation sample dries to form a highly viscous liquid.
Cette invention a trait à un procédé de séchage de prélèvements biologiques et autres prélèvements instables, permettant de les conserver sous forme de liquides à haute viscosité. Le procédé consiste à préparer un prélèvement à protéger par dissolution et/ou mise en suspension d'un agent actif dans une solution contenant un agent de stabilisation, à soumettre ce prélèvement aux effets d'une température et d'une pression telles que le solvant s'évapore et ce, sans congélation ni formation de bulles, afin d'obtenir une mousse et à extraire le solvant jusqu'à ce que le prélèvement sèche en formant un liquide à haute viscosité.
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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