Dual-chamber chromatographic cartridge

B - Operations – Transporting – 01 – D

Patent

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Details

B01D 15/08 (2006.01)

Patent

CA 2594604

A chromatography cartridge with a packed bed is manufactured from an inner and outer chamber (11), the inner chamber being in an insert (12) that is slidable into the outer chamber (11) with openings in each such that a slurry that is originally placed in the interior of the outer chamber (11) as the parts are being pressed into each other. During the assembly, the particles in the slurry are compressed to fill the smaller volume of the inner chamber and excess liquid is discharged through ports in both chambers. The construction allows for a highly precise and reproducible column filling process with a minimum of steps and operator intervention and thereby low cost and reduced error.

L'invention concerne une cartouche chromatographique présentant un lit conditionné, formée d'une chambre interne et d'une chambre externe, la chambre interne se trouvant dans un insert pouvant être glissé dans la chambre externe, chacune présentant des ouvertures permettant à une pâte initialement placée à l'intérieur de la chambre externe de s'écouler dans la chambre interne lorsque les pièces sont comprimées l'une dans l'autre. Au cours de l'assemblage, les particules de la pâte sont comprimées de manière à remplir le plus petit volume de la chambre interne et l'excès de liquide est évacué par des orifices pratiqués dans les deux chambres. Cette configuration permet un processus de remplissage de colonne reproductible hautement précis avec un minimum d'étapes et d'interventions de la part de l'opérateur, et, par conséquent, un moindre coût et une réduction d'erreurs.

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