Dual component bis-biguanide containing dentifrice of...

A - Human Necessities – 61 – K

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A61K 8/73 (2006.01) A61K 8/21 (2006.01) A61K 8/29 (2006.01) A61K 8/34 (2006.01) A61K 8/43 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2494397

A dual component chlorhexidine dentifrice composition of improved shelf stability in which the first component is a gel containing a bis-biguanide antibacterial agent in which the gel vehicle is thickened with a cellulose polymer and the second component is a paste containing a silica abrasive wherein the bis-biguanide antibacterial agent provides undiminished antiplaque and antigingivitis effect with reduced staining when the physically separated components are combined and mixed upon application to dental tissue.

L'invention concerne une composition de dentifrice à deux composants renfermant de la chlorhexidine et possédant une stabilité de conservation améliorée. Le premier composant de cette composition est un gel renfermant un agent anti-bactérien à base de bis-biguanide, le véhicule de celui-ci étant épaissi au moyen d'un polymère de cellulose, et le second composant est une pâte renfermant un abrasif à base de silice, l'agent anti-bactérien à base de bis-biguanide conférant un effet non diminué anti-plaque et anti-gingivite à coloration réduite quand les composants physiquement séparés sont combinés et mélangés au moment de l'application sur le tissu dentaire.

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