Dual-functional nonfouling surfaces and materials

Details Dual-functional nonfouling surfaces and materials Dual-functional nonfouling surfaces and materials

C - Chemistry, Metallurgy

08

G

C08G 73/02 (2006.01) C07K 17/08 (2006.01) C08F 8/00 (2006.01) C08F 20/34 (2006.01) C08F 20/54 (2006.01) C08F 26/02 (2006.01) G01N 33/53 (2006.01) C07K 1/22 (2006.01) C40B 40/04 (2006.01) C40B 80/00 (2006.01)

Patent

CA 2674632

Dual-functional nonfouling surfaces and materials, methods for making dual- functional nonfouling surfaces and materials, and devices that include dual-functional nonfouling surfaces and materials. The dual-functional surfaces are nonfouling surfaces that resist non-specific protein adsorption and cell adhesion. The dual-functional surfaces and materials include covalently coupled biomolecules (e.g., target binding partners) that impart specific biological activity thereto. The surfaces and materials are useful in medical diagnostics, biomaterials and bioprocessing, tissue engineering, and drug delivery.

L'invention concerne des surfaces anti-salissure bifonctionnelles et des matériaux, des procédés pour former des surfaces anti-salissure bifonctionnelles et des matériaux, et des dispositifs comprenant des surfaces anti-salissure bifonctionnelles et des matériaux. Les surfaces bifonctionnelles sont des surfaces anti-salissure résistant à l'adsorption de protéine non spécifique et à l'adhésion de cellules. Les surfaces bifonctionnelles et les matériaux comprennent des biomolécules couplées de manière covalente (par exemple, des partenaires de liaison cible) conférant une activité biologique spécifique à ceux-ci. Les surfaces et matériaux sont utiles dans les diagnostics médicaux, les biomatériaux et le biotraitement, le génie tissulaire et l'administration de médicament.

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