Dual pharmacophores - pde4 -muscarinic antagonistics

C - Chemistry – Metallurgy – 07 – D

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Details

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) A61K 31/551 (2006.01) A61P 11/00 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2714418

The present invention relates to novel compounds of Formula (I) and their use in the treatment of respiratory diseases, including anti-inflammatory and allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.

La présente invention concerne de nouveaux composés représentés par la formule (I) et leur utilisation dans le traitement de maladies respiratoires, notamment des maladies anti-inflammatoires et allergiques telles que les maladies pulmonaires obstructives chroniques (MPOC), l'asthme, la rhinite (par exemple la rhinite allergique), la dermatite atopique ou le psoriasis.

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