Dual specificity antibody fusions

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/00 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01)

Patent

CA 2700714

The present invention provides dual specificity antibody fusion proteins comprising an antibody Fab or Fab' frag-ment with specificity for an antigen of interest, said fragment being fused to at least one single domain antibody which has specificity for a second antigen of interest.

La présente invention porte sur des protéines de fusion d'anticorps à double spécificité, comprenant un fragment Fab ou Fab' d'anticorps ayant une spécificité pour un antigène d'intérêt, ledit fragment étant fusionné à au moins un anticorps à domaine unique qui a une spécificité pour un second antigène d'intérêt.

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