Dye intermediate and method

Details Dye intermediate and method Dye intermediate and method

C - Chemistry, Metallurgy

09

B

C09B 57/00 (2006.01) C07C 227/08 (2006.01) C07C 229/18 (2006.01) C07C 303/32 (2006.01) C07C 309/49 (2006.01) C09B 11/24 (2006.01) C09B 23/01 (2006.01) C09B 23/06 (2006.01) C09B 23/14 (2006.01) C09B 47/00 (2006.01) C09B 57/02 (2006.01)

Patent

CA 2297215

Various classes of dyes are provided having acid, ester or amide groups for covalent linking to biomolecules. The dyes may be prepared by use of a compound of formula (I) where R1 comprises a linker and a carboxy including acid, salt, ester including N-hydroxysuccinimide, activated ester or amide group; R2, R3, R4 and R5 are H, C1-C10 alkyl or aralkyl or a group to modify solubility or electronic or spectral properties or a functional linking group: or R4-R5 and/or R2-R4 and/or R2-R3 are linked to form an extended ring system; and R6 is H or CHO or NO.

L'invention concerne différentes classe de colorants comportant des groupes acide, ester ou amide formant une liaison covalente avec les biomolécules. Ces colorants peuvent être préparés avec un composant représenté par la formule (I), dans laquelle R?1¿ comprend un élément de liaison et un carboxy, notamment un acide, un sel, un ester, notamment un N-hydroxysuccinimide, un ester activé ou un groupe amide; R?2¿, R?3¿, R?4¿ et R?5¿ sont H, l'alkyle C¿1?-C¿10? ou l'aralkyle ou un groupe servant à modifier la solubilité ou les propriétés électroniques ou spectrale, ou un groupe de liaison fonctionnel; ou R?4¿-R?5¿ et/ou R?2¿-R?4¿ et/ou R?2¿-R?3¿ sont liés pour former un système cyclique étendu; et R?6¿ est H ou CHO ou NO.

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