Dynamic genomic deletion expansion and formulation of...

Details Dynamic genomic deletion expansion and formulation of... Dynamic genomic deletion expansion and formulation of...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2585025

Provided are materials, methods, platforms, and kits for diagnosing, prognosing, and/or determining the biological aggressiveness of a tumor (malignant and non-malignant) based in part on the temporal profile of genomic deletion expansion of the tumor. Also provided are methods of determining marker panels for different diseases and/or tissues and markers identified by these methods.

La présente invention concerne des matériaux, des procédés, des plates-formes et des nécessaires permettant de faire un diagnostic, un pronostic et/ou une évaluation de l'agressivité biologique d'une tumeur maligne ou bénigne, en partie sur la base du profil temporel de l'expansion des suppression génomiques de la tumeur. L'invention concerne également, d'une part des procédés permettant de déterminer des jeux de marqueurs pour différentes affections et/ou différents tissus, et d'autre part des marqueurs identifiés par ces procédés.

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