(-)e-2-(3,4-dichlorocinnamyl)-1-cyclopropylmethyl-piperidine...

Details (-)e-2-(3,4-dichlorocinnamyl)-1-cyclopropylmethyl-piperidine... (-)e-2-(3,4-dichlorocinnamyl)-1-cyclopropylmethyl-piperidine...

C - Chemistry, Metallurgy

07

D

C07D 211/18 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2277839

(-)E-2-(3,4-dichlorocinnamyl) -1-cyclopropylmethyl-piperidine of formula (I) and its addition salts with pharmaceutically acceptable acids; their use as antidiarrhoeals in mammals; pharmaceutical compositions intended for treatment of diarrhoeas.

L'invention a pour objet le (-)E-2-(3,4-dichlorocinnamyl)-1-cyclopropylméthyl-piperidine présentant la formule (I) et ses sels d'addition avec des acides pharmaceutiquement acceptables. L'invention traite aussi de leur utilisation comme antidiarrhéiques chez le mammifère, et de compositions pharmaceutiques prévues pour traiter les diarrhées.

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