(e)-3-¬1-n-butyl-5-¬2-(2-carboxyphenyl)methoxy-4-chloropheny...

Details (e)-3-¬1-n-butyl-5-¬2-(2-carboxyphenyl)methoxy-4-chloropheny... (e)-3-¬1-n-butyl-5-¬2-(2-carboxyphenyl)methoxy-4-chloropheny...

C - Chemistry, Metallurgy

07

D

C07D 405/02 (2006.01) A61K 31/415 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2312965

This invention relates to a new monoargininyl salt form of the endothelin receptor antagonist, (E)-3-[1-n-Butyl-5- [2-(2-carboxyphenyl)methoxy-4- chlorophenyl]- 1H-pyrazol-4-yl]-2- [(5-methoxy-2,3-dihydrobenzofuran- 6- yl)methyl]-prop-2-enoic acid.

L'invention concerne une nouvelle forme de sel monoargininylique de l'antagoniste du récepteur de l'endothéline, (E)-3-[1-n-Butyl- 5[2(2-carboxyphényl)méthoxy-4- chlorophényl]- 1H-pyrazol-4-yl]-2- [(5-méthoxy-2,3-dihydrobenzofuran-6-yl)méthyl]- prop-2-énoïque.

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