E,3-dihydroestra-1,3,5(10)-trieno-(16.alpha.,17.alpha.-.beta...

Details E,3-dihydroestra-1,3,5(10)-trieno-(16.alpha.,17.alpha.-.beta... E,3-dihydroestra-1,3,5(10)-trieno-(16.alpha.,17.alpha.-.beta...

C - Chemistry, Metallurgy

07

J

260/13

C07J 71/00 (2006.01) C07J 17/00 (2006.01)

Patent

CA 1039268

Abstract of the Disclosure Novel 2',3'-dihydroestra-1,3,5(10)-trieno[16.alpha., 17.alpha.-b]furan-17.beta.-ols, useful in the treatment of menopausal syndrome and other conditions of estrogen deficiency, are described herein. These compounds are prepared by cyclizing a corresponding 17.alpha.-ethynyl-estroil in the presence of a base.

231679

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