C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/70 (2006.01) C07K 14/245 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 15/13 (2006.01)
Patent
CA 2502152
The present invention provides an Ecoli host cell expressing a recombinant antibody characterized in that the Ecolihost cell has been genetically modified in order to change at least one physical property of one or more Ecoli proteins which in the wild type co~purify with said recombinant antibody.
L'invention concerne une cellule hôte E.coli exprimant un anti-corps recombinant. La cellule hôte E.coli se caractérise en ce qu'elle a été génétiquement modifiée pour changer au moins une propriété physique d'une ou de plusieurs protéines E.coli qui, lorsqu'elles sont du type sauvage, sont copurifiées avec l'anticorps recombinant.
Chapman Andrew Paul
Humphreys David Paul
Robinson Martyn Kim
Spitali Mariangela
Celltech R. & D. Limited
Robic
Ucb Pharma S.a.
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