Early detection of sepsis

Details Early detection of sepsis Early detection of sepsis

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12M 1/34 (2006.01) C40B 30/04 (2006.01) C40B 60/00 (2006.01) G01N 33/483 (2006.01) A61B 5/00 (2006.01) C40B 30/02 (2006.01) G01N 15/14 (2006.01) G01N 33/68 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2587270

The invention describes a system and method for detecting early signs of infection and, in particular, for identifying individuals most likely to develop sepsis. Measurement of expression levels of particular combinations of cytokines and/or cellular activation markers, optionally combined with the use of predictive algorithms, allows a high degree of accuracy of prediction. The method is applicable in both civilian and military contexts.

La présente invention concerne un système et un procédé pour détecter des signes précurseurs d'une infection et, en particulier, pour identifier des individus plus susceptibles de développer une sepsie. Une mesure des niveaux d'expression de combinaisons particulières de cytokines et/ou de marqueurs d'activation cellulaire, éventuellement combinée à l'utilisation d'algorithmes prédictifs, permet d'obtenir un degré de précision élevé de prévision. Ce procédé peut s'appliquer à la fois dans des contextes civils et dans des contextes militaires.

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