Easily absorbed oral preparations of xanthine derivatives

Details Easily absorbed oral preparations of xanthine derivatives Easily absorbed oral preparations of xanthine derivatives

A - Human Necessities

61

K

A61K 31/522 (2006.01) A61K 47/12 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2633372

An object of the present invention is to provide an easily absorbable oral preparation containing a xanthine derivative or a pharmaceutically acceptable salt thereof and a fatty acid or a fatty acid derivative for the purpose of providing an easily absorbable oral preparation containing the xanthine derivative of which absorbability has been enhanced by dissolving the xanthine derivative that shows adenosine A1 receptor antagonistic activity and has diuretic activity, kidney-protecting activity, bronchodilating activity, cerebral function-improving activity, anti-dementia activity or the like in a solvent.

L'invention concerne une préparation orale facilement absorbée contenant un dérivé de la xanthine laquelle présente un antagonisme vis-à-vis du récepteur A1 de l'adénosine et a un effet diurétique, un effet néphroprotecteur, un effet bronchodilatateur, un effet d'amélioration du fonctionnement du cerveau, un effet anti-démence et similaires, dans laquelle le dérivé de la xanthine est dissous dans un solvant ce qui améliore de cette manière son absorbabilité. L'invention concerne la préparation orale facilement absorbée contenant le dérivé de la xanthine ou un sel acceptable du point de vue pharmaceutique de celui-ci et un acide gras ou un dérivé d'acide gras.

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