Eb matrix production from animal tissue and its use for...

A - Human Necessities – 61 – L

Patent

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A61L 27/38 (2006.01) A01N 1/02 (2006.01) A61K 35/12 (2006.01) A61K 35/14 (2006.01) A61L 27/36 (2006.01)

Patent

CA 2468310

A method of fonning and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue to chemical and mechanical processing. In addition to skin tissue, another source of EBM is a blood vessel. EBM may be used for hernia repair, colon, rectal, vaginal and or urethral prolapse treatment; pelvic floor reconstruction; muscle flap reinforcement; lung tissue support; rotator cuff repair Qr replacement; periosteum replacement; dura repair; pericardial membrane repair; soft tissue augmentation; intervertebral disk repair; and periodontal repair. EBM may also be used as a urethral sling, laminectomy barrier or spinal fusion device.

L'invention concerne un procédé de formation et de conservation d'un matériau biopolymère squelette, pouvant être remodelé biologiquement, consistant à soumettre un tissu animal à un traitement chimique et mécanique. Outre la peau, les vaisseaux sanguins constituent une autre source d'EBM. L'EBM peut être utilisée pour la réparation de hernie, pour le traitement de prolapsus du colon, rectal, vaginal ou urétral, reconstruction du plancher pelvien, renforcement du lambeau musculaire, comme support de tissu pulmonaire, en remplacement ou réparation de muscle périarticulaire, en remplacement du périoste, en réparation de la dure-mère, en réparation de la membrane du péricarde, pour l'augmentation de tissu mou, en réparation de disque intervertébral, et en réparation parodontale. L'EBM peut aussi être utilisée en tant qu'élingue urétrale, barrière de laminectomie ou dispositif de fusion de vertèbres.

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