Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/113 (2010.01) A61K 31/713 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 17/00 (2006.01) C12N 15/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2697513

The present invention relates to methods for treating or preventing lung cancer by administering a double-stranded molecule against one or more of EBI3, DLX5, NPTX1, CDKN3 or EF-I delta genes or compositions, vectors or cells containing such a double-stranded molecule. The present invention also features methods for diagnosing lung cancer, especially NSCLC or SCLC, using one or more over-expressed genes selected from among EBI3, DLX5, NPTX1, CDKN3 and/or EF-I delta. Also disclosed are methods of identifying compounds for treating and preventing lung cancer, using as an index their effect on the over-expression of one or more of EBI3, DLX5, CDKN3 and/or EF-I delta in the lung cancer, the cell proliferation function of one or more of EBI3, DLX5, NPTX1, CDKN3 and/or EF-I delta or the interaction between CDKN3 and VRS, EF-I beta, EF-I gamma and/or EF-I delta.

La présente invention porte sur des procédés pour traiter ou prévenir le cancer du poumon par administration d'une molécule double brin à l'encontre d'un ou plusieurs parmi les gènes EBI3, DLX5, NPTX1, CDKN3 ou EF-1 delta ou de compositions, vecteurs ou cellules contenant une telle molécule double brin. La présente invention porte également sur des procédés pour diagnostiquer le cancer du poumon, en particulier NSCLC ou SCLC, à l'aide d'un ou plusieurs gènes surexprimés choisis parmi EBI3, DLX5, NPTX1, CDKN3 et/ou EF-1 delta. L'invention porte également sur des procédés d'identification de procédés pour traiter et prévenir le cancer du poumon, en utilisant, comme indice, leur effet sur la surexpression d'un ou plusieurs parmi EBI3, DLX5, CDKN3 et/ou EF-1 delta dans le cancer du poumon, la fonction de prolifération des cellules d'un ou plusieurs parmi EBI3, DLX5, CDKN3 et/ou EF-1 delta ou l'interaction entre CDKN3 et VRS, EF-1 béta, EF-1 gamma et/ou EF-1 delta.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ebi3, dlx5, nptx1 and cdkn3 for target genes of lung cancer... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-2061575

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.